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VTE Prophylaxis Education Implementation Project


This project focuses on implementing findings from a completed PCORI study, which showed that a single, web-based nurse education module can have a dramatic effect on missed doses of VTE prophylaxis administration (blood clot prevention) in hospitalized patients. It also showed that a patient-centered education bundle delivered to hospitalized patients reduces missed doses by nearly 50%. 

The primary objective is to help nurses and patients make informed decisions regarding VTE prevention and reduce the occurrence of blood clots in injured patients. Our aims are: 

  • To implement the validated nurse education module, and patient-centered education tool at 10 trauma centers in an existing research hospital network (CLOTT) 
  • To examine data on missed and refused doses of VTE prophylaxis and study the intervention’s impact on VTE outcomes in trauma patients at high-risk for VTE events 
  • To conduct a qualitative study to tailor the intervention to the different health care settings and computer systems so that it can be implemented nationally 

The intervention will be implemented in 3 steps: 1) all bedside nurses will complete the online, interactive, scenario-based education module; 2) the electronic alert will be built into each site’s electronic health record (EHR) system; and 3) the patient-centered education bundle and real-time alert will launch. 

This work is funded through a Patient-Centered Outcomes Research Institute (PCORI) Dissemination and Implementation Award (DI-2019C3-17859).

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