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Recent Publications Resulting from CNTR Studies

 

PublicationPublish Year
Guido JM, Krause M, Steiner A, Nicol A, Grider KT, Wong GZ, et al. Trauma community clinical guidance needs: a mixed-methods iterative consensus-building study. Trauma Surgery & Acute Care Open. 2025;10:e001592. https://doi.org/10.1136/tsaco-2024-0015922025
Wong GZ, Panshin MS, Samsamshariat T, Albirair M, Gamboa JE, Simmons CG, et al. Dissecting inequity: global systematic review of trauma clinical guidance. Trauma Surgery & Acute Care Open. 2025;10:e001624. https://doi.org/10.1136/tsaco-2024-0016242025
Steiner A, Person MA, Bowe DD, Johnson A, Wong GZ, Senturia K, et al. Understanding the rural injury providers’ experiences with trauma clinical guidance: a qualitative case series. Trauma Surgery & Acute Care Open. 2025;10:e001598. https://doi.org/10.1136/tsaco-2024-0015982025
Wilson DJ, Wong GZ, Tignanelli C, Nix M, Moreno AN, LaGrone LN. TRAUMA: making trauma clinical guidance more implementable. Trauma Surgery & Acute Care Open. 2025;10:e001610. https://doi.org/10.1136/tsaco-2024-0016102025
Wilson DJ, Gellings JA, Zavala G, Steiner A, Kwan BM, Bixby PJ, et al. Conference Proceedings for the 2024 Design for Implementation: The Future of Trauma Research and Clinical Guidance Conference Series. Trauma Surgery & Acute Care Open. 2025;10:e001583. https://doi.org/10.1136/tsaco-2024-0015832025
Lang KL, Bixby PJ, Price MA, Villarreal CL, Moreno AN, LaGrone LN. The Design for Implementation: The Future of Trauma Research and Clinical Guidance (DFI) Conference Series Editorial. Trauma Surgery & Acute Care Open. 2025;10:e001582. https://doi.org/10.1136/tsaco-2024-0015822025
Alexandra MP Brito, MB, ChB, BAO, Jonathan P. Meizoso, MD, MSPH, Todd Costantini, MD. Research priorities in tranexamic acid after trauma: Secondary analysis of the National Trauma Research Action Plan. J Trauma Acute Care Surg. Vol 97, No. 4. DOI: 10.1097/TA.00000000000043582024
Bulger EM, Bixby PJ, Price MA, Villarreal CL, Moreno AN, Herrera-Escobar JP, Bailey JA, Brasel KJ, Cooper ZR, Costantini TW, Gibran NS, Groner JI, Joseph BA, Newgard CD, Stein DM. An executive summary of the National Trauma Research Action Plan (NTRAP). Journal of Trauma and Acute Care Surgery (e ahead of print) doi: 10.1097/TA.0000000000004279.2024
Price, Michelle A, PhD, Villarreal, Cynthia Lizette, MA, Moreno, Ashley N, MS, Flayter, Rochelle, MSN, Herrera-Escobar, Juan Pablo, MD, MPH, Simes, Carrie A, MD, Bulger, Eileen M, MD, and the NTRAP Regulatory Challenges Panel. Developing a National Trauma Research Action Plan (NTRAP): Results from the Regulatory Challenges Delphi Survey. Journal of Trauma and Acute Care Surgery, 2024; 96(4), DOI: 10.1097/TA.00000000000041852024
Medrano NW, Villarreal CL, Price MA, Bixby PJ, Bulger EM, Eastridge BJ, MIMIC Study Group. Access to Trauma Center Care: A Statewide System-Based Approach. The Journal of Trauma and Acute Care Surgery, 2023.2023
Costantini TW, Bulger E, Price MA, Haut ER. Research Priorities in Venous Thromboembolism after Trauma: Secondary Analysis of the National Trauma Research Action Plan (NTRAP). J Trauma Acute Care Surg. June 16, 20232023
Villarreal CL, Price, MA, Moreno AN, Zenteno, A, Saenz C, Toppo A, Herrera-Escobar JP, Sims CA, Bulger EM, and the NTRAP Investigators Group. Regulatory Challenges in Conducting Human Subjects Research in Emergency Settings: The National Trauma Research Action Plan (NTRAP) Scoping Review. Trauma Surgery and Acute Care Open. 2023.2023
Asanthi Ratnasekera, William Geerts, Elliott R. Haut, Michelle Price, Todd Costantini, Patrick Murphy. Implementation science approaches to optimizing venous thromboembolism prevention in patients with traumatic injuries: Findings from the 2022 Consensus Conference to Implement Optimal Venous Thromboembolism Prophylaxis in Trauma. J Trauma Acute Care Surg. 2022 Dec 6;94(3):490–494. doi: 10.1097/TA.00000000000038502023
Morgan Schellenberg MD, MPH, Todd Costantini MD, Bellal Joseph MD, Michelle A. Price PhD, Andrew C. Bernard MD, Elliott R. Haut MD, PhD. TIMING OF VENOUS THROMBOEMBOLISM (VTE) PROPHYLAXIS INITIATION AFTER INJURY: FINDINGS FROM THE CONSENSUS CONFERENCE TO IMPLEMENT OPTIMAL VTE PROPHYLAXIS IN TRAUMA. J Trauma Acute Care Surg. 2023 Mar 1;94(3):484-489. doi: 10.1097/TA.00000000000038472023
Elliott R. Haut MD, PhD, FACS, James P. Byrne, MD, PhD, Michelle A. Price, PhD, Pamela Bixby, MA, Eileen M. Bulger, MD, FACS, Leslie Lake, Todd Costantini, MD, FACS. Proceedings from the 2022 Consensus Conference to Implement Optimal Venous Thromboembolism (VTE) Prophylaxis in Trauma. Journal of Trauma and Acute Care Surgery, Journal of Trauma and Acute Care Surgery 94(3):p 461-468, March 2023. DOI: 10.1097/TA.00000000000038432023
Navpreet K Dhillon, MD, Elliott R Haut, MD, PhD, Michelle A Price, PhD, Todd W Costantini, MD, Amanda L Teichman, MD, Bryan A Cotton, MD, MPH, Eric Ley, MD. Novel Therapeutic Medications for Venous Thromboembolism Prevention in Trauma Patients: Findings from the Consensus Conference to Implement Optimal VTE Prophylaxis in Trauma. Journal of Trauma and Acute Care Surgery 94(3):p 479-483, March 2023. | DOI: 10.1097/TA.00000000000038532023
Amanda L. Teichman, MD, FACS, Bryan A. Cotton, MD, MPH, James Byrne, MD, Navpreet K. Dhillon, MD, Allison E., Berndtson, MD, FACS, Michelle A. Price, PhD, Tracy A. Johns, MSN, Eric J. Ley, MD, Todd Costantini, MD, Elliott Haut, MD, PhD. Approaches for Optimizing Venous Thromboembolism (VTE) Prevention in Injured Patients: Findings from the Consensus Conference to Implement Optimal VTE Prophylaxis in Trauma. Journal of Trauma and Acute Care Surgery 94(3):p 469-478, March 2023. | DOI: 10.1097/TA.00000000000038542023
Godat et al: Venous thromboembolism risk after spinal cord injury: a secondary analysis of the CLOTT study. Journal of Trauma and Acute Care Surgery 2022; 94; 23.2022
Knudson et al: Tissue plasminogen activator resistance is an early predictor of posttraumatic venous thromboembolism: a prospective study from the CLOTT research group. J Trauma Acute Care Surgery. 2022;93: 597.2022
Knudson et al: Challenging Traditional Paradigms in Posttraumatic Pulmonary Thromboembolism. JAMA Surgery December 2022.2022
Herrera-Escobar JP, Reidy E, Phuong J, Brasel KJ, Cuschieri J, Fallat M, et al. Developing a National Trauma Research Action Plan: Results from the long-term outcomes research gap Delphi survey. Journal of Trauma and Acute Care Surgery. 2022;93(6):854-62.2022
Brasel KJ, Braverman MA, Phuong J, Price MA, Kaplan LJ, Kozar R, et al. Developing a National Trauma Research Action Plan: Results from the postadmission critical care research gap Delphi survey. Journal of Trauma and Acute Care Surgery. 2022;93(6):846-53.2022
Cooper, Zara MD, MSc; Herrera-Escobar, Juan P. MD, MPH; Phuong, Jimmy PhD; Braverman, Maxwell A. DO; Bonne, Stephanie MD; Knudson, Mary Margaret MD; Rivara, Frederick P. MD; Rowhani-Rahbar, Ali MD, MPH, PhD; Price, Michelle A. PhD; Bulger, Eileen M. MD; the NTRAP Injury Prevention Panel. Developing a National Trauma Research Action Plan: Results from the injury prevention research gap Delphi survey. Journal of Trauma and Acute Care Surgery 93(3):p 367-375, September 2022. DOI: 10.1097/TA.00000000000036652022
Gibran, Nicole S. MD, FACS; Shipper, Edward MD; Phuong, Jimmy PhD; Braverman, Max MD; Bixby, Pam MA; Price, Michelle A. PhD; Bulger, Eileen M. MD, FACS; on behalf of the NTRAP Burns & Reconstructive Surgery Panel Group. Developing a national trauma research action plan: Results from the Burn Research Gap Delphi Survey. Journal of Trauma and Acute Care Surgery 92(1):p 201-212, January 2022. DOI: 10.1097/TA.00000000000034092022
Costantini, Todd W. MD, et al. Developing a National Trauma Research Action Plan: Results from the acute resuscitation, initial patient evaluation, imaging, and management research gap Delphi survey. Journal of Trauma and Acute Care Surgery: August 2022 - Volume 93 - Issue 2 - p 200-2082022
Joseph, Bellal MD, et al. Developing a National Trauma Research Action Plan: Results from the geriatric research gap Delphi survey. Journal of Trauma and Acute Care Surgery: August 2022 - Volume 93 - Issue 2 - p 209-2192022
Medrano NW, Villarreal CL, Mann NC, Price MA, Nolte, KB, MacKenzie, EJ, Bixby P, Eastridge BJ, MIMIC Study Group (2022). Activation and on-scene intervals for severe trauma EMS interventions: An analysis of the NEMSIS database, Prehospital Emergency Care, April 2022. April 2022
DOI: 10.1080/10903127.2022.2053615
2022
Groner, Jonathan I. MD, et al. Developing a National Trauma Research Action Plan (NTRAP) Results from the Pediatric Research Gap Delphi Survey. Journal of Trauma and Acute Care Surgery Vol. 93, No. 3, September 2022.2022
Stein, Deborah M. MD, MPH, et al. Developing a National Trauma Research Action Plan: Results from the Neurotrauma Research Panel Delphi Survey. Journal of Trauma and Acute Care Surgery: May 2022 - Volume 92 - Issue 5 - p 906-9152022
Newgard, Craig D. MD, MPH, et al. Developing a National Trauma Research Action Plan: Results from the prehospital and mass casualty research Delphi survey. Journal of Trauma and Acute Care Surgery: February 2022 - Volume 92 - Issue 2 - p 398-4062022
Siletz, Anaar, MD, PhD, Blair, Kevin, Cooper, Richelle, MD, MSHS, Nguyen, N., et al. (2021). A pilot study of stored low titer group O whole blood + component therapy versus component therapy only for civilian trauma patients. Journal of Trauma and Acute Care Surgery, 91, 655-662. https://doi.org/10.1097/TA.00000000000033342021
Orlas, Claudia P. MD; Thomas, Arielle MD; Herrera-Escobar, Juan P. MD, MPH; Price, Michelle A. PhD; Haider, Adil H. MD, MPH; Bulger, Eileen M. MD; The National Trauma Research Action Plan (NTRAP) Investigators Group. Long-term Outcomes of Firearm Injury Survivors in the United States: The National Trauma Research Action Plan Scoping Review. Journal of Trauma and Acute Care Surgery. Vol, 92 No. 52021
Juan P. Herrera-Escobar, MD MPH; Michelle A. Price, PhD; Emma Reidy, MPH; Pamela J. Bixby; Kaman Hau; Eileen M. Bulger, MD; Adil H. Haider, MD MPH; and the National Trauma Research Action Plan (NTRAP) Investigators Group. Core Outcome Measures for Research in Traumatic Injury Survivors: The NTRAP Modified Delphi Consensus Study. Accepted for publication in the Annals of Surgery, August 20212021
TJ Milling, S Warach, SC Johnston, BJ Gajewski, T Costantini, et al. Restart TICrH Trial Design: an adaptive randomized trial of time intervals to restart direct oral anticoagulants after traumatic intracranial hemorrhage. Journal of Neurotrauma, January 2021. doi: 10.1089/neu.2020.75352021
Herrera-Escobar JP*, Osman SY*, Das S, Toppo A, Orlas CP, Castillo-Angeles M, Rosario A, Janjua MB, Abdullah Arain M, Reidy E, Jarman MP, Nehra D, Price MA, Bulger EM, Haider AH, and the National Trauma Research Action Plan (NTRAP) Investigators Group. Long-term Patient-Reported Outcomes and Patient-Reported Outcome Measures after Injury: The National Trauma Research Action Plan (NTRAP) Scoping Review. J Trauma Acute Care Surg. 2021.2021
King B, Milling TJ, Gajewski B, Costantini T, Wick Jo, Price MA, Mudaranthakam D, Stein D, Connolly S, Valadka A, Warach, S. Restarting and timing of oral anticoagulation after traumatic intracranial hemorrhage: A review and summary of ongoing and planned prospective randomized clinical trials. Trauma Surgery and Acute Care Open. 2020;5:e000605. PMCID: PMC77166762020
Herrera-Escobar JP, Castillo-Angeles M, Osman SY, Orlas CP, Janjua MB, Abdullah Arain M, Reidy E, Jarman MP, Price MA, Bulger EM, Nehra D, Haider AH, and the National Trauma Research Action Plan (NTRAP) Investigators Group. Long-term Patient-Reported Outcomes Measures after Injury: The National Trauma Research Action Plan (NTRAP) Scoping Review Protocol. Trauma Surg Acute Care Open. 2020:5(1):E0005122020
Joseph V. Sakran, Hiba Ezzeddine, C. William Schwab, Bellal Joseph, Barbara Gaines, David Livingston, Karen Brasel, Lillian Kao, Sam Mandell, Deepika Nehra, Erin Hall, Adil Haider, Mark Seamon, Brad Kurowski, Nicole Gibran, Joseph T. Giacino, Joseph Cuschieri, James Ficke, Stephanie Bonne, Juan Herrera-Escobar, Babak Sarani, Peter Yonclas, Ben Zarzaur, Randall Burr, Eileen Bulger, Avery Nathens and The Patient Reported Outcome Consortium.* Proceedings from the Consensus Conference on Trauma Patient Reported Outcome Measures. Journal of the American College of Surgeons. May 2020; 230(5); doi:10.1016/j.jamcollsurg.2020.01.0322020
Godat LN, Jensen AR, Stein DM and The Coalition for National Trauma Research Scientific Advisory Council. Patient centered outcomes research and the injured patient: A summary of application. Trauma Surgery and Acute Care Open. Feb 2020; 5:e000422. doi:10.1136/tsaco-2019-0004222020
Ho VA, Dicker RA, Haut ER and The Coalition for National Trauma Research Scientific Advisory Council.* Dissemination, Implementation, and De-Implementation: The Trauma Perspective. Trauma Surgery and Acute Care Open. Feb 2020; 5:e000423. doi:10.1136/tsaco-2019-000423.2020
Harvin J, Zarzaur B, Nirula R, King B, Malhotra A, and The Coalition for National Trauma Research Scientific Advisory Council. Alternative Clinical Trials Designs. Trauma Surgery and Acute Care Open. Feb 2020; 5: e000420. doi:10.1136/tsaco-2019-000420. 2020
Price MA, Kozar RA, Bulger EM, Jurkovich JG, and The Coalition for National Trauma Research Scientific Advisory Council. Building the future for national trauma research. Trauma Surgery and Acute Care Open. Feb 2020; 5: e000421. doi:10.1136/tsaco-2019-000421.2020
Jay Doucet, M.D., Paula Ferrada M.D., Sarah Murthi M.D., Ram Nirula M.D., Sara Edwards M.D., Emily Cantrell, M.D., Jinfeng Han, Daniel Haase M.D., Andrew Singleton M.D., Katie Birkas M.Sc., Giovanna Casola, M.D., Raul Coimbra, M.D., Ph.D. Ultrasonographic IVC Diameter Response to Trauma Resuscitation After One Hour Predicts 24 Hour Fluid Requirement. Journal of Trauma. Pending Publication, 2019.2020
Medrano NW, Villarreal CL, Price MA, MacKenzie E, Nolte KB, Phillips MJ, Stewart RM, Eastridge BJ. Multi-Institutional Multi-Disciplinary Injury Mortality Investigation in the Civilian Pre-hospital Environment (MIMIC): A methodology for reliably measuring pre-hospital time and distance to definitive care. Trauma Surgery and Acute Care Open. Vol. 4:1. January 2019; 4:e000309. doi:10.1136/tsaco-2019-000309.2019
Michelle A Price, Pam J Bixby, Monica J Phillips, Gregory J Beilman, Eileen M Bulger, Michael R Davis, Matthew J McAuliffe, Todd E Rasmussen, Jose Salinas, Sharon L Smith, Mary Ann Spott, Leonard J Weireter, Donald H Jenkins. Launch of the National Trauma Research Repository coincides with new data sharing requirements. Trauma Surgery and Acute Care Open, 2018, 3: e000193.2018
Eileen M. Bulger, MD, Todd E. Rasmussen, MD, Gregory J. Jurkovich, MD, Timothy C. Fabian, MD, Rosemary A. Kozar, MD, Raul Coimbra, MD, Todd W. Costantini, MD, James Ficke, MD, Ajai K. Malhotra, MD, Michelle A. Price, PhD, Sharon L. Smith, MS, William G. Cioffi, MD, and Ronald M. Stewart, MD. Implementation of a National Trauma Research Action Plan (NTRAP). J Trauma Acute Care Surg Volume 84, Number 6.2018
Faulconer, E. R., et al. (2018). "Use of open and endovascular surgical techniques to manage vascular injuries in the trauma setting: A review of the American Association for the Surgery of Trauma PROspective Observational Vascular Injury Trial registry." Journal of Trauma and Acute Care Surgery 84(3): 411-417.2018
Loja MN, Galante JM, Humphries M, Savage S, Fabian T, Scalea T, Holcomb JB, Poulin N, DuBose J, Rasmussen TE; AAST PROOVIT Study Group. Systemic anticoagulation in the setting of vascular extremity trauma. Injury. 2017 Sep;48(9):1911-1916.2017
Loja MN, DuBose J, Sammam A, Li CS, Liu Y, Savage S, Scalea TM, Holcomb JB, Rasmussen TE, Knudson MM, AAST PROOVIT Study Group. The Mangled extremity score and amputation: Time for a revision. J Trauma Acute Care Surg. 2017 Mar;82(3):518-523.2017
Coimbra R, Kozar RA, Smith JW, Zarzaur BL, Hauser CJ, Moore FA, Bailey JA, Valadka A., Jurkovich GJ, Jenkins DH, Davis KA, Price MA, Maier RV. The Coalition for National Trauma Research supports the call for a national trauma research action plan. J Trauma Acute Care Surg. 2017 Mar; 82(3):637-645.2017
Siletz, Anaar MD, PhD; Burruss, Sigrid MD; Gruber, Terry MS; Ziman, Alyssa MD; Marder, Victor MD; Cryer, Henry Magill MD, PhD Leukocyte filtration lesion impairs functional coagulation in banked whole blood. Journal of Trauma and Acute Care Surgery: September 2017 - Volume 83 - Issue 3 - p 420–426. 2017
Zarzaur BL, Dunn JA, Leininger B, Lauerman M, Shanmuganathan K, Kaups K, Zamary K, Hartwell JL, Bhakta A, Myers J, Gordy S, Todd SR, Claridge JA, Teicher E, Sperry J, Privette A, Allawi A, Burlew CC, Maung AA, Davis KA, Cogbill T, Bonne S, Livingston DH, Coimbra R, Kozar RA. Natural history of splenic vascular abnormalities after blunt injury: A Western Trauma Association multicenter trial. J Trauma Acute Care Surg. 2017 Dec;83(6):999-1005.2017
National Trauma Institute Research Group, Price MA, Beilman GJ, Fabian TC, Hoyt DB, Jurkovich GJ, Knudson MM, MacKenzie EJ, Marshall VS, Overton KE, Peitzman AB, Phillips MJ, Pruitt BA, Smith SL, Stewart RM, Jenkins DJ. The National Trauma Institute: Lessons learned in the funding and conduct of 16 trauma research studies. J Trauma Acute Care Surg. 2016;81: 548–554.2016